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Botanical Name :Bacopa monnieri
Sanskrit name : Brahmi, Nira-brahmi
English Name : Thyme-Leaved Gratiola
Family : Scrophulariaceae
Plant Parts Used : Whole plant
Description of Bacopa monnieri:
A small, creeping herb, its stems are obtuse-angular; the leaves are short-petioled, cuneate to obovate; the capsules are ovoid. It can be easily grown in damp areas and can be propagated using seeds or vegetatively. Commonly growing in marshy places throughout India, ascending to an altitude of 1,320 m.
Principal Constituents:
The herb contains the alkaloids brahmine, herpestine, and a mixture of
three bases. It also contains the saponins, monnierin ; hersaponin,
bacoside A and bacoside B. Other constituents present in the plant are
D-mannitol, betulic acid, ß- sitosterol, stigmasterol and its esters,
heptacosane, octacosane, nonacosane, triacontane, hentriacontane,
dotriacontane, nicotine, 3-formyl-4-hydroxy-2H-pyran, luteolin and its
7-glucoside. The presence of a-alamine, aspartic acid, glutamic acid and
serine is also reported
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Pharmacology:
The saponin, hersaponin, is reported to possess cardiotonic, sedative
and spasmodic properties. It produced a mild inhibitory effect on the
respiration of rat brain tissue which was partially reduced by LSD-25
and potentiated by 5-HT. It was also found, as in the case of reserpine,
to deplete nor-adrenaline and 5-HT content of the rat brain. An
alcoholic extract of the plant, in a dose of 50mg/kg, produced a
tranquilizing effect on albino rats and dogs but the action was weaker
than that produced by chlorpromazine. An ethanolic extract (50%) of the
plant exhibited anticancer activity against the Walker carcinosarcoma
256 in rats. The administration of an aqueous suspension of an alcoholic
extract (40mg/kg, p.o.) for three or more days is reported to improve
the performance of rats in various learning situations.
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Medicinal Uses:
The entire plant constitutes the well-known drug Brahmi. It is astringent, bitter and cooling, and, is reported to improve the intellect. It is used in indigenous systems of medicine for the treatment of asthma, hoarseness, insanity, epilepsy and as a potent nerve tonic, cardiotonic and diuretic. A clinical report showed that this drug is an anti-anxiety agent having adaptogenic effect. It exhibits a barbiturate hypnosis-potentiating effect in albino rats. The leaves are also useful as a diuretic and aperient
The entire plant constitutes the well-known drug Brahmi. It is astringent, bitter and cooling, and, is reported to improve the intellect. It is used in indigenous systems of medicine for the treatment of asthma, hoarseness, insanity, epilepsy and as a potent nerve tonic, cardiotonic and diuretic. A clinical report showed that this drug is an anti-anxiety agent having adaptogenic effect. It exhibits a barbiturate hypnosis-potentiating effect in albino rats. The leaves are also useful as a diuretic and aperient
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BACOPA MONNIERA ( BRAHMI, PENNYWORT )
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PRODUCT CODE: | NE/BM/022 | ||
DESCRIPTION
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LIGHT GREEN TO BROWN COLOURED DRY POWDER WITH BITTER
TASTE.
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ODOUR | CHARACTERISTIC | ||
SOLUBILITY
ALCOHOL 50.0% V/V |
MIN. 50% |
||
PH 1% W/V SOLN. | 3~7 | ||
LOSS ON DRYING | 7% MAX | ||
ACTIVE
INGREDIENTS BACCOSIDES |
20% MIN |
40% MIN |
60% MIN |
HEAVY METALS | 20 PPM MAX | ||
ARSENIC | 5 PPM MAX | ||
TOTAL PLATE COUNT | 1000 CFU/ GM MAX | ||
TOTAL YEAST MOULD | 100 CFU/GM MAX | ||
E. COLI, SALMONELLA | ABSENT | ||
S. AEREUS | ABSENT |
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*Disclaimer
"These statements have not been evaluated by the food and drug administration or any other regulatory body. These products are not intended to diagnose, treat, cure, or prevent any
disease.
"These statements have not been evaluated by the food and drug administration or any other regulatory body. These products are not intended to diagnose, treat, cure, or prevent any
disease.
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