Wednesday 14 August 2013

Bacopa monnieri Brahmi, Nira-brahmi ,Thyme-Leaved Gratiola


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Botanical Name :Bacopa monnieri
Sanskrit name : Brahmi, Nira-brahmi
English Name :
Thyme-Leaved Gratiola 
Family
Scrophulariaceae
Plant Parts Used : Whole plant


Description of Bacopa monnieri:
A small, creeping herb, its stems are obtuse-angular; the leaves are short-petioled, cuneate to obovate; the capsules are ovoid. It can be easily grown in damp areas and can be propagated using seeds or vegetatively. Commonly growing in marshy places throughout India, ascending to an altitude of 1,320 m.




Principal Constituents:
The herb contains the alkaloids brahmine, herpestine, and a mixture of three bases. It also contains the saponins, monnierin ; hersaponin, bacoside A and bacoside B. Other constituents present in the plant are D-mannitol, betulic acid, ß- sitosterol, stigmasterol and its esters, heptacosane, octacosane, nonacosane, triacontane, hentriacontane, dotriacontane, nicotine, 3-formyl-4-hydroxy-2H-pyran, luteolin and its 7-glucoside. The presence of a-alamine, aspartic acid, glutamic acid and serine is also reported


Pharmacology:
The saponin, hersaponin, is reported to possess cardiotonic, sedative and spasmodic properties. It produced a mild inhibitory effect on the respiration of rat brain tissue which was partially reduced by LSD-25 and potentiated by 5-HT. It was also found, as in the case of reserpine, to deplete nor-adrenaline and 5-HT content of the rat brain. An alcoholic extract of the plant, in a dose of 50mg/kg, produced a tranquilizing effect on albino rats and dogs but the action was weaker than that produced by chlorpromazine. An ethanolic extract (50%) of the plant exhibited anticancer activity against the Walker carcinosarcoma 256 in rats. The administration of an aqueous suspension of an alcoholic extract (40mg/kg, p.o.) for three or more days is reported to improve the performance of rats in various learning situations. 
 

Medicinal Uses:
The entire plant constitutes the well-known drug Brahmi. It is astringent, bitter and cooling, and, is reported to improve the intellect. It is used in indigenous systems of medicine for the treatment of asthma, hoarseness, insanity, epilepsy and as a potent nerve tonic, cardiotonic and diuretic. A clinical report showed that this drug is an anti-anxiety agent having adaptogenic effect. It exhibits a barbiturate hypnosis-potentiating effect in albino rats. The leaves are also useful as a diuretic and aperient




 
BACOPA MONNIERA ( BRAHMI, PENNYWORT )
PRODUCT CODE: NE/BM/022
DESCRIPTION
LIGHT GREEN TO BROWN COLOURED DRY POWDER WITH BITTER TASTE.
ODOUR CHARACTERISTIC
SOLUBILITY
ALCOHOL 50.0% V/V

MIN. 50%
PH 1% W/V SOLN. 3~7
LOSS ON DRYING 7% MAX
ACTIVE INGREDIENTS
 BACCOSIDES

20% MIN

40% MIN

60% MIN
HEAVY METALS 20 PPM MAX
ARSENIC 5 PPM MAX
TOTAL PLATE COUNT 1000 CFU/ GM MAX
TOTAL YEAST MOULD 100 CFU/GM MAX
E. COLI, SALMONELLA ABSENT
S. AEREUS ABSENT



 *Disclaimer
   "These statements have not been evaluated by the food and drug administration or any other regulatory body. These products are not intended to diagnose, treat, cure, or prevent any
    disease.

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